Biomarkers and their relation to cardiac function late after peripartum cardiomyopathy

Angiogenic imbalance involving the placental protein soluble Fms-like tyrosine kinase-1 (sFlt-1) and cleavage of the nursing-hormone prolactin by the enzyme cathepsin D (CD) both play a role in the pathogenesis of peripartum cardiomyopathy (PPCM). We hypothesized that angiogenic imbalance and increased activity of CD have a long-lasting impact in women with PPCM.

https://www.onlinejcf.com/article/S1071-9164(21)00002-6/fulltext?rss=yes

Source: Journal of Cardiac Failure - January 7, 2021 Category: Cardiology Authors: Anne S. Ersb øll, Jens P. Goetze, Marianne Johansen, Maria G. Hauge, Karen Sliwa, Niels Vejlstrup, Finn Gustafsson, Peter Damm Source Type: research