LysR Family regulator LttR Controls Conjugated Linoleic Acid Production by Directly Activating the cla Operon in Lactobacillus plantarum.

This study reveals a new regulatory mechanism in CLA biotransformation and provides a new potential metabolic engineering strategy to increase the yield of CLA.Importance Our work has identified a novel transcriptional regulator LTTR that regulates the production of CLA by activating the transcription of cla-dh and cla-dc, essential genes participating in the CLA synthesis in Lactobacillus plantarum This provides the insight into the regulatory mechanism of CLA synthesis and broadens our understanding about synthesis and regulatory mechanisms of biosynthesis of CLA. PMID: 33397697 [PubMed - as supplied by publisher]
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research