A novel long intergenic non-coding RNA, Nostrill, regulates iNOS gene transcription and neurotoxicity in microglia

Microglia are resident immunocompetent and phagocytic cells in the CNS. Pro-inflammatory microglia, stimulated by microbial signals such as bacterial lipopolysaccharide (LPS), viral RNAs, or inflammatory cytok...

Source: Journal of Neuroinflammation - January 6, 2021 Category: Neurology Authors: Nicholas W. Mathy, Olivia Burleigh, Andrew Kochvar, Erin R. Whiteford, Matthew Behrens, Patrick Marta, Cong Tian, Ai-Yu Gong, Kristen M. Drescher, Peter S. Steyger, Xian-Ming Chen and Annemarie Shibata Tags: Research Source Type: research