CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress.

CONCLUSIONS: These findings suggest that CERKL may be important in cSCC progression and could lead to novel strategies for prevention and treatment of cSCC.
PMID: 33393080 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - January 4, 2021 Category: Dermatology Authors: Meyer JM, Lee E, Celli A, Park K, Cho R, Lambert W, Pitchford M, Gordon M, Tsai K, Cleaver J, Arron ST, Mauro TM Tags: Br J Dermatol Source Type: research