Unilateral Relapsing Primary Angiitis of the CNS: An Entity Suggesting Differences in the Immune Response Between the Cerebral Hemispheres
Conclusions
Combining our 3 cases with others reported in the literature allows better clinical understanding about this rare and extremely puzzling disease entity. We hypothesize that a functional difference in immune responses, caused by such discrepancies as basal levels of cytokines, asymmetric distribution of microglia, and differences in modulation of the systemic immune functions, rather than a structural antigenic difference, between the right and left brain may explain this phenomenon, but this is speculative.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: AbdelRazek, M. A., Hillis, J. M., Guo, Y., Martinez-Lage, M., Gholipour, T., Sloane, J., Cho, T., Matiello, M. Tags: All Immunology, Autoimmune diseases, Vasculitis, Infarction Article Source Type: research
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