The effect of β 3 -adrenoceptor gene polymorphisms on lower urinary tract function in males

ConclusionThe Trp64Arg variant of the β3-adrenoceptor gene significantly increased PVR and voiding time in men. However, it was not significantly associated with the emergence of LUTS. Thus, since the effect of β3-adrenoceptor gene polymorphisms on the genitourinary organs might be weak, whether men possess the Trp64Arg variant of the β3-adrenoceptor gene might not critically affect urinary quality of life, but modestly affect the lower urinary tract function.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research