Knockdown EZH2 attenuates cerebral ischemia-reperfusion injury via regulating microRNA-30d-3p methylation and USP22.

CONCLUSION: Silencing EZH2 suppresses miR-30d-3p methylation and then ameliorates oxidative stress and nerve injury via regulating USP22 in cerebral I/R injury mice, which may be a potential candidate for treatment of cerebral I/R injury. PMID: 33388376 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33388376?dopt=Abstract

Source: Brain Research Bulletin - December 31, 2020 Category: Neurology Authors: Jin D, Wei W, Song C, Han P, Leng X Tags: Brain Res Bull Source Type: research