Estimates of Alpha/Beta ( α/β) Ratios for Individual Late Rectal Toxicity Endpoints: An Analysis of the CHHiP trial

Changes in fraction size of external beam radiotherapy (EBRT) exert non-linear impacts on subsequent toxicity. Commonly described by the linear-quadratic model, fraction size sensitivity of normal tissues is expressed by the α/β ratio. Here we study individual α/β ratios for different late rectal side effects after prostate EBRT.

Source: International Journal of Radiation Oncology * Biology * Physics - January 4, 2021 Category: Radiology Authors: Douglas H. Brand, Sarah C. Br üningk, Anna Wilkins, Katie Fernandez, Olivia Naismith, Annie Gao, Isabel Syndikus, David P. Dearnaley, Alison C. Tree, Nicholas van As, Emma Hall, Sarah Gulliford, CHHiP Trial Management Group Tags: Physics Contribution Source Type: research