Intraneural electrical stimulation of median nerve: a simulation study on sensory and motor fascicles.

Intraneural electrical stimulation of median nerve: a simulation study on sensory and motor fascicles. J Biol Regul Homeost Agents. 2020 Sep-Oct;34(5 Suppl. 3):127-136. Technology in Medicine Authors: Stefano M, Cordella F, Zollo L Abstract Neuroprostheses can be an innovative solution to improve quality of life of upper limb amputees. In this framework, the recovery of sensory feedback is a property widely requested by amputee subjects. Neural prostheses are based on neural interfaces that allow delivering direct current stimuli to the nerve fibers. The study of the interaction between the nerve and the electrode is fundamental to investigate activation properties in the nerve. Furthermore, the results could provide useful insight into improve the design of the electrodes and to advance and ameliorate tactile sensations, elicited by these interfaces, obtaining tactile feedback more like natural sensations. This work aims at studying, by means of a FEM Neuron computational model, the axon fibers activation by means of neural stimulation provided through the intraneural electrodes DS-file. Three different types of stimulation waveforms (i.e. biphasic charge balanced stimulus with inter-pulse delay, biphasic charge balanced stimulus without inter-pulse delay, biphasic charge unbalanced stimulus with inter-pulse delay), three different nerve fascicles, i.e. two sensory and one motor fascicle, and ten distances from the electrode in the ...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research