Dual versus triple therapy for uncomplicated brucellosis: A retrospective cohort study

Conclusions: Due to lack of differences in clinical outcomes, mortality, length of stay, and end of therapy parameters between the two groups, a regimen comprising two, rather than three, agents can be sufficient for uncomplicated brucellosis. This finding conforms to previous studies. Therefore, replacing rifampin with an aminoglycoside for its presumed superior efficacy as per the World Health Organization ' s guidelines is not substantiated by our study. Further studies with a larger sample size are required to confirm these findings.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research