Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis.

This study highlights the critical interaction of FOXM1 and SMAD3 for controlling TGF-β signaling during metastasis.
PMID: 24382352 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - January 2, 2014 Category: Cancer & Oncology Authors: Xue J, Lin X, Chiu WT, Chen YH, Yu G, Liu M, Feng XH, Sawaya R, Medema RH, Hung MC, Huang S Tags: J Clin Invest Source Type: research