Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1.

CONCLUSIONS: The excellent potency, safety and synergistic profiles of this potent first-in-class Hec1-targeted small molecule TAI-1 show its potential for clinically utility in anti-cancer treatment regimens.
PMID: 24401611 [PubMed - as supplied by publisher]

Source: Clinical Breast Cancer - January 9, 2014 Category: Cancer & Oncology Authors: Huang LY, Lee YS, Huang JJ, Chang CC, Chang JM, Chuang SH, Kao KJ, Tsai YJ, Tsai PY, Liu CW, Lin HS, Lau JY Tags: J Exp Clin Cancer Res Source Type: research