Consideration regarding immune checkpoint inhibitor –induced secondary adrenal insufficiency in patients lacking human leucocyte antigen-DR15

We read the article entitled ‘Human leucocyte antigen DR15, a possible predictive marker for immune checkpoint inhibitor-induced secondary adrenal insufficiency’ by Seiichi Yano et al. [1] with great interest. The authors reported significantly higher prevalence of human leucocyte antigen (HLA)-DR15, B52, and Cw12 in 11 pa tients with immune checkpoint inhibitor (ICPi)–induced secondary adrenal insufficiency as compared with Japanese healthy controls. Furthermore, they presented the possibility of HLA-DR15 as a predictive marker of a pituitary immune-related adverse event (irAE).
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Letter to the Editor Source Type: research