The hematological parameters and biochemical markers of iron status in alfa-thalassemia 3.7kb deletion from metropolitan region of manaus, amazonas, brazil.

Conclusion:The alfa-thal prevalence corroborates with other Brazilians studies. Molecular diagnosis is important to prevent the most severe forms of the disease, thus epidemiological studies using molecular tools become extremely important in regions where the disease is underestimated. In this context, this is the first study that reports ?-thalassemia deletion in the population from State of Amazonas. Our findings are relevant because they have impact in the clinical therapeutic choice and also demonstrate the importance of differential diagnosis between genetic anemia and iron deficiency anemia.

Source: Mediterranean Journal of Hematology and Infectious Diseases - December 31, 2020 Category: Hematology Authors: Fernanda Cozendey Anselmo, Abdou Gafar Soumanou , Cleidiane de Aguiar Ferreira , Flora Maia Viga Sobrinha, Ana Caroline Santos Castro, Rafael Oliveira Brito, Adolfo Jos é Mota, Marilda de Souza Gonçalves, Jose Pereira Moura Neto Source Type: research