Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome.

Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome. Br J Dermatol. 2020 Dec 24;: Authors: Jerjen R, Koh WL, Sinclair R, Bhoyrul B Abstract Loose anagen hair syndrome (LAHS) is a sporadic or autosomal dominant hair disorder which typically affects girls aged 2-6 years.1 It is characterised by increased hair shedding, non-scarring alopecia, inability to grow long hair, dull and lustreless hair. Premature and defective keratinisation of the inner root sheath (IRS), and impaired anchorage of anagen hairs underlie the pathogenesis.1 A favourable response has been demonstrated in three patients with LAHS treated with topical minoxidil.1-3 Low-dose oral minoxidil (LDOM) has been shown to be effective in adult androgenetic alopecia, alopecia areata and telogen effluvium.4 Herein we describe the efficacy and safety of LDOM in LAHS. PMID: 33368146 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research