Preparation and encapsulation techniques of chitosan microsphere for enhanced bioavailability of natural antioxidants.

This article discusses possible solutions to improve the bioavailability using several preparation and encapsulation techniques for microspheres using chitosan as a carrier. The first is the emulsion technique that controls particle size (0.5-1000 μm) according to the speed (RPM) of the agitator. The second technique discussed is spray drying-a very simple method that can control particle size (5-5000 μm) according to the nozzle size and discharge pressure. The third is the extrusion technique, which can control particle size (250-2500 μm) according to the syringe pore size. These techniques have enormous potential for use as drug delivery systems (DDS) in the functional food and biomedical field industries.
PMID: 33358143 [PubMed - as supplied by publisher]

Source: Carbohydrate Research - December 16, 2020 Category: Genetics & Stem Cells Authors: Nah JW, Jeong GW Tags: Carbohydr Res Source Type: research