Role of group 3 innate lymphoid cells in antibody production.

Role of group 3 innate lymphoid cells in antibody production.
Curr Opin Immunol. 2015 Jan 23;33C:36-42
Authors: Magri G, Cerutti A
Abstract
Innate lymphoid cells (ILCs) constitute a heterogeneous family of effector lymphocytes of the innate immune system that mediate lymphoid organogenesis, tissue repair, immunity and inflammation. The initial view that ILCs exert their protective functions solely during the innate phase of an immune response has been recently challenged by evidence indicating that ILCs shape adaptive immunity by establishing both contact-dependent and contact-independent interactions with multiple hematopoietic and non-hematopoietic cells, including B cells. Some of these interactions enhance antibody responses both systemically and at mucosal sites of entry.
PMID: 25621842 [PubMed - as supplied by publisher]

Source: Current Opinion in Immunology - January 23, 2015 Category: Allergy & Immunology Authors: Magri G, Cerutti A Tags: Curr Opin Immunol Source Type: research