Association of Neutrophil-to-Lymphocyte Ratio with Non-calcified Coronary Artery Burden in Psoriasis: Findings from an Observational Cohort Study

Inflammation in the form of elevated high-sensitivity c-reactive protein (hs-CRP) has been shown to be critical in the development of atherothrombosis. Psoriasis, a chronic inflammatory skin disease, is associated with high systemic-inflammation, elevated neutrophil-to-lymphocyte ratio (NLR) and accelerated non-calcified coronary artery burden (NCB) by coronary computed tomography angiography (CCTA). We hypothesized that NLR would associate with early, rupture-prone atherosclerosis assessed as NCB independent of hs-CRP.

Source: Journal of Cardiovascular Computed Tomography - December 27, 2020 Category: Radiology Authors: Amit K. Dey, Heather L. Teague, Nicholas H. Adamstein, Justin A. Rodante, Martin P. Playford, Marcus Y. Chen, David A. Bluemke, Joel M. Gelfand, Paul M. Ridker, Nehal N. Mehta Tags: Research paper Source Type: research