Pregnancy in pulmonary arterial hypertension: Midterm outcomes of mothers and offspring

Before the turn of the century, pregnancy in women with pulmonary arterial hypertension (PAH) was associated with maternal mortality rates of 30% and neonatal mortality rates of 11%.1 In more recent series, despite improved management of PAH, pregnancy-associated maternal mortality remained high, ranging from 11% to 25%.2 –6 As of today, there is no cure for PAH, and case reports have suggested that pregnancy may accelerate disease progression.7 Hence, current pulmonary hypertension guidelines continue to recommend that all patients with PAH avoid pregnancy.

Source: The Journal of Heart and Lung Transplantation - December 11, 2020 Category: Transplant Surgery Authors: Jan C. Kamp, Constantin von Kaisenberg, Susanne Greve, Lotta Winter, Da-Hee Park, Jan Fuge, Christian K ühn, Marius M. Hoeper, Karen M. Olsson Tags: RESEARCH CORRESPONDENCE Source Type: research