Biological Significance of Anti-SARS-CoV-2 Antibodies: Lessons Learned From Progressive Multifocal Leukoencephalopathy
Conclusion
Based on pathogenic lessons learned from PML under natalizumab therapy, we suggest the incorporation of functional assays that determine neutralizing properties of SARS-CoV-2–specific antibodies. In addition, we outline the potential role of T-cell detection assays in determining herd immunity in a given population or in studying therapeutic responses to vaccines.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Manouchehri, N., Steinman, L., Stuve, O. Tags: All Immunology, Viral infections, COVID-19, Multiple sclerosis Article Source Type: research
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