Staphylococcal hemolytic potential is correlated with increased severity of atopic dermatitis in children and young adults

Atopic dermatitis (AD) represents a complex intersection between skin barrier dysfunction, host immunologic response, and external factors such as allergenic triggers and the skin microbiome. However, the relative contributions of these factors is not clear. There is a surge in Staphylococcus aureus on skin during flares of AD (Kong et al., 2012). S. aureus strains seen in AD flares are unique to the host and capable of eliciting varied immune responses (Byrd et al., 2017). No direct relationship between severity and in vitro toxin genotype has been established (Kim et al., 2009).
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Letters to the Editor Source Type: research