The effect of a 6-month Ketogenic Medium-Chain Triglyceride Supplement on Plasma Cardiometabolic and Inflammatory Markers in Mild Cognitive Impairment.

Mild cognitive impairment (MCI) is a major risk factor for Alzheimer's disease (AD) with an reported annualized conversion rate ranging from 5-17% per person-year [1] depending on the MCI subtypes and the presence of the APOE4 allele [2]. By definition, cognitive decline in MCI does not significantly affect daily functioning but does involve below normal results in at least one cognitive domain compared to healthy age-matched older people. MCI is often accompanied by metabolic abnormalities such as insulin resistance and comorbidities such as dyslipidemia and hypertension [3, 4].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Source Type: research