Angiotensin II and Amyloid- β Synergistically Induce Brain Vascular Smooth Muscle Cell Senescence.
CONCLUSIONS: Ang II and Aβ synergistically promoted BVSMC senescence at least due to enhancement of the p-ERK-p16-pRb signaling pathway, oxidative stress and NF-κB/IκB activity.
PMID: 33349854 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - Category: Cardiology Authors: Bai HY, Min LJ, Shan BS, Iwanami J, Kan-No H, Kanagawa M, Mogi M, Horiuchi M Tags: Am J Hypertens Source Type: research