Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy

Conclusions: The intermediate metabolizer genotype was more common than the extensive and poor metabolizer genotypes in our study sample. We recommended further studies to investigate the risk of efavirenz underexposure and overexposure in carries of the extensive and poor metabolizer genotypes respectively in our patient population.

Source: Nigerian Journal of Clinical Practice - December 23, 2020 Category: Rural Health Authors: AO Isaac DD Wetkos AO Oche I Godwin K Phyllis AC John Source Type: research