Primary Leiomyosarcoma of the Mandible in a Child

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Tags: Case Reports Source Type: research

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Conclusions: These results provide new insights into the pathogenesis, diagnosis, treatment, and prognosis of sarcomas and provide new directions for further study of sarcoma.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: October 2020Source: Journal of Comparative Pathology, Volume 180Author(s): Fábio S Mendonça, Givaldo B Silva Filho, Hisadora A C Bom, Silvio M C Fonseca, Marcio A Silva, Luciana C Rameh-de-Albuquerque, Julian Beingesser, Francisco A Uzal
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
Authors: Miyake M, Oda Y, Nishimura N, Morizawa Y, Ohnishi S, Hatakeyama K, Fujii T, Hori S, Gotoh D, Nakai Y, Anai S, Torimoto K, Tsukamoto S, Fujii H, Kido A, Honoki K, Matsumura Y, Okajima E, Tanaka N, Fujimoto K Abstract Evidence is limited regarding the immunologic profile and immune microenvironment of soft tissue sarcoma subtypes. The aim of the present study was to describe the clinical significance and prognostic implications of PD-L1, PD-L2, and PD-1 in patients with retroperitoneal sarcoma (RSar). In this retrospective, multicenter, collaborative study, medical charts were reviewed and the immunohistoche...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
n R Abstract Leiomyosarcoma (LMS) in the sinonasal tract (SNT) is a rarity that has been firstly described in 1958. Since then, there have been only a few articles about this entity. Most of the data available about LMS in the SNT is derived from case reports. We believe that our case will support the data set and help guiding the management of this rare condition. A 84-year-old female presented with nasal airway obstruction on the left side. She experienced several episodes of epistaxis from her left nostril, what made her to seek medical care. A rhinoscopy revealed an obstructing mass in the left nasal cavity. C...
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
Conditions:   Epstein-Barr Virus (EBV)-Associated Diseases;   EBV+ Lymphoproliferative Disease With Primary Immunodeficiency (PID LPD);   EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (AID LPD);   EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous Syste m (CNS PTLD);   EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD);   Solid Organ Transplant Complications;   Lymphoproliferative Disorders;   Allogeneic Hematopoietic Cell Transplant;   Stem Cell Transplant&nb...
Source: - Category: Research Source Type: clinical trials
Authors: de Sande González LM, Martin-Broto J, Kasper B, Blay JY, Le Cesne A Abstract INTRODUCTION: The efficacy and tolerability of trabectedin in patients with soft tissue sarcoma (STS) have been confirmed by various clinical studies involving lipo- and leiomyosarcomas as well as many other subtypes including translocation-related sarcomas. These data have been obtained from randomized phase II and III clinical trials. Studies in real-world clinical practice are necessary to bridge the efficacy-effectiveness gap and complete the body of evidence. Furthermore, reinforcing clinical experience with data from ...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
Publication date: November 2020Source: Urology Case Reports, Volume 33Author(s): Manint Usawachintachit, Julin Opanuraks, Jerasit Surintrspanont, Kroonpong Iampenkhae, Apirak Santingamkun
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
PMID: 32950243 [PubMed - as supplied by publisher]
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
ean-Yves Blay Franck Tirode A series of 42 patient tumors diagnosed as endometrial stromal sarcoma (ESS) based on the morphology but negative for JAZF1 and/or YWHAE rearrangement in FISH was analyzed by RNA-sequencing. A chromosomal rearrangement was identified in 31 (74%) of the cases and a missense mutation in known oncogenes/tumor suppressor genes in 11 (26%). Cluster analyses on the expression profiles from this series together with a control cohort composed of five samples of low grade ESS harboring a JAZF1-SUZ12 fusion, one high grade ESS harboring a BCOR-ITD, two uterine tumors resembling ovarian sex cord tumo...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
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