Haloperidol potentiates antinociceptive effects of morphine and disrupt opioid tolerance.

In conclusion, haloperidol enhances the antinociceptive effects of morphine without significant adverse effects, as it is able to disrupt or delay the morphine-tolerance in neuropathic pain. PMID: 33347818 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33347818?dopt=Abstract

Source: European Journal of Pharmacology - December 18, 2020 Category: Drugs & Pharmacology Authors: Mena-Valdés LC, Blanco-Hernández Y, Espinosa-Juárez JV, López-Muñoz FJ Tags: Eur J Pharmacol Source Type: research