Secondary metabolites from Lantana camara L. flowers extract exhibit in  vivo anti-urolithiatic activity in adult Wistar albino rats.

Secondary metabolites from Lantana camara L. flowers extract exhibit in vivo anti-urolithiatic activity in adult Wistar albino rats.
Nat Prod Res. 2020 Dec 21;:1-4
Authors: Ezzat MI, El Gendy SN, Saad AS, Abdo WS, El Sayed AM, Elmotayam AK
Abstract
The present study aims at evaluating potential of the ethanol extracts of L. camara leaves (LE), flowers (FlE) and roots (RE) in the treatment of renal calculi and characterising the secondary metabolites in the active extract. The results revealed that the FlE had significantly reduced the levels of kidney parameters (calcium, creatinine, urea, and uric acid) against ethylene glycol (EG) injuries, and restored the activity of glutathione peroxidase (GPx), superoxide dismutase and lipid peroxide malondialdehyde to the normal level. In addition, FlE significantly attenuated iNOS tissue expression caused by EG. The results obtained in this study suggest the potential value of the L. camara L. flowers as an antiurolithiatic agent.
PMID: 33342292 [PubMed - as supplied by publisher]

Source: Natural Product Research - December 21, 2020 Category: Biochemistry Authors: Ezzat MI, El Gendy SN, Saad AS, Abdo WS, El Sayed AM, Elmotayam AK Tags: Nat Prod Res Source Type: research