Malaysian outcome of acute necrotising encephalopathy of childhood

Acute necrotizing encephalopathy (ANE) is a rare and often a devasting form of acute encephalopathy among children [1]. ANE was first proposed by Mizuguchi et al and was considered to be a parainfectious disease that is triggered mainly by viral infections [2]. Whilst the underlying etiology and disease pathogenesis remain mostly unknown, studies have highlighted that proinflammatory cytokines and soluble cytokine receptors causing a ‘cytokine storm’ plays an important role in the pathogenesis of this disease [3].

Source: Brain and Development - December 21, 2020 Category: Neurology Authors: Choong Yi Fong, Mon Thandar Saw, Limin Li, Wei Kang Lim, Lai Choo Ong, Chin Seng Gan Tags: Original article Source Type: research