Mechanism of Naringenin Blocking the Protection of LTB4/BLT1 Receptor Against Septic Cardiac Dysfunction.

CONCLUSION: Naringenin inhibits LTB4/BLT1 receptors to attenuate cardiomyocyte inflammation and apoptosis, which may mediate the protective effect of anti-septic cardiac dysfunction by activating AMPK signaling pathway and inhibiting NF-κB signaling and mitochondrial damage. PMID: 33334792 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33334792?dopt=Abstract

Source: Annals of Clinical and Laboratory Science - November 1, 2020 Category: Laboratory Medicine Authors: Ye G, Wang M, Liu D, Cheng L, Yin X, Zhang Q, Liu W Tags: Ann Clin Lab Sci Source Type: research