microRNA-103a-3p confers protection against lipopolysaccharide-induced sepsis and consequent multiple organ dysfunction syndrome by targeting HMGB1.

CONCLUSIONS: Taken together, our results demonstrated the inhibitory role of miR-103a-3p in sepsis via inhibiting HMGB1 expression.
PMID: 33333289 [PubMed - as supplied by publisher]

Source: Infection, Genetics and Evolution - December 14, 2020 Category: Genetics & Stem Cells Authors: Li Y, Zhu H, Pan L, Zhang B, Che H Tags: Infect Genet Evol Source Type: research