Ethnic and age-specific acute lung injury/acute respiratory distress syndrome risk associated with angiotensin-converting enzyme insertion/deletion polymorphisms, implications for COVID-19: A meta-analysis.

CONCLUSIONS: Significant associations of the ACE I/D polymorphism with the risk of ALI/ARDS were indicated in Caucasians and children as well as in Asians in mortality analysis. These findings were underpinned by high significance, high statistical power and robustness. ACE genotypes may be useful for ALI/ARDS therapy for patients with COVID-19.
PMID: 33338639 [PubMed - as supplied by publisher]

Source: Infection, Genetics and Evolution - December 15, 2020 Category: Genetics & Stem Cells Authors: Pabalan N, Tharabenjasin P, Suntornsaratoon P, Jarjanazi H, Muanprasat C Tags: Infect Genet Evol Source Type: research