Feeding difficulties in children and adolescents with spinal muscular atrophy type 2

Spinal muscular atrophy (SMA) is a progressive neuromuscular disorder caused by a homozygous deletion of the SMN1 gene, or rarely by compound heterozygosity with smaller SMN1 mutations [1]. SMA is characterized by the degeneration of alpha motor neurons in the anterior horn of the spinal cord. SMA is classified into four different subtypes (types 1-4) based on the highest achieved motor milestone [2].

Source: Neuromuscular Disorders - December 18, 2020 Category: Neurology Authors: Renske I. Wadman, Ramona De Amicis, Chiara Brusa, Alberto Battezzati, Simona Bertoli, Tracey Davis, Marion Main, Adnan Manzur, Chiara Mastella, Pinki Munot, Nadia Imbrigiotta, Lucia Schottlaender, Anna Sarkozy, Federica Trucco, Giovanni Baranello, Mariacr Source Type: research