OUTSTEP ‐HF: Randomised controlled trial comparing short‐term effects of sacubitril/valsartan versus enalapril on daily physical activity in patients with chronic heart failure with reduced ejection fraction

ConclusionAfter 12  weeks of treatment, there was no significant benefit of sacubitril/valsartan on either 6MWT or in daytime physical activity measured by actigraphy compared with enalapril. (ClinicalTrials.gov number, NCT02900378).

Source: European Journal of Heart Failure - December 13, 2020 Category: Cardiology Authors: Massimo F. Piepoli, Rizwan I. Hussain, Josep Comin ‐Colet, Ramon Dosantos, Philippe Ferber, Tiny Jaarsma, Frank Edelmann Tags: Research Article Source Type: research