The Effects of Monosodium Glutamate on PSMA Radiotracer Uptake in Men with Recurrent Prostate Cancer: A Prospective, Randomized, Double-Blind, Placebo-Controlled Intraindividual Imaging Study
Conclusion: Orally administered MSG significantly decreased salivary gland, kidney, and other normal-organ PSMA radiotracer uptake in human subjects, using 18F-DCFPyL as an exemplar. However, MSG caused a corresponding reduction in tumor uptake, which may limit the benefits of this approach for diagnostic and therapeutic applications.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Harsini, S., Saprunoff, H., Alden, T., Mohammadi, B., Wilson, D., Benard, F. Tags: Clinical Source Type: research
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