Effects of low-load/high-repetition resistance training on exercise capacity, health status and limb muscle adaptation in patients with severe COPD: a randomized controlled trial.

Effects of low-load/high-repetition resistance training on exercise capacity, health status and limb muscle adaptation in patients with severe COPD: a randomized controlled trial.
Chest. 2020 Dec 11;:
Authors: Nyberg A, Martin M, Saey D, Milad N, Patoine D, Morissette M MC, Auger D, Stål P, Maltais F
Abstract
BACKGROUND: Training volume is paramount in the magnitude of physiological adaptations following resistance training. However, patients with severe COPD are limited by dyspnea during traditional two-limb low-load/high-repetition resistance training (LLHR-RT), resulting in sub-optimal training volumes. During a single exercise session, single-limb LLHR-RT decreases the ventilatory load and enables higher localized training volumes compared to two-limb LLHR-RT.
RESEARCH QUESTION: Does single-limb LLHR-RT lead to more profound effects when compared to two-limb LLHR-RT on exercise capacity (6-minute walk distance [6MWD]), health status, muscle function and limb intramuscular adaptations in patients with severe COPD?
STUDY DESIGN AND METHODS: Thirty-three patients (66±7 years; FEV1 39±10% pred) were randomized to eight-weeks of single- or two-limb LLHR-RT. Exercise capacity (6MWD), health status, and muscle function were compared between groups. Quadriceps muscle biopsies were collected to examine physiological responses.
RESULTS: Single-limb LLHR-RT did not further enhance 6MWD when compared to two-limb (Î...

Source: Chest - December 11, 2020 Category: Respiratory Medicine Authors: Nyberg A, Martin M, Saey D, Milad N, Patoine D, Morissette M MC, Auger D, Stål P, Maltais F Tags: Chest Source Type: research