Long non-coding RNA GAS5 retards neural functional recovery in cerebral ischemic stroke through modulation of the microRNA-455-5p/PTEN axis.

CONCLUSION: This work elucidates that GAS5 downregulation upregulates miR-455-5p to repress PTEN expression, in turn attenuating IS, which may broaden the horizon of IS treatment. PMID: 33309710 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research