Bridging the age gap in breast cancer. Impacts of omission of breast cancer surgery in older women with oestrogen receptor positive early breast cancer. A risk stratified analysis of survival outcomes and quality of life

For the majority of older women with early ER+  breast cancer, surgery is oncologically superior to PET. In less fit, older women, with characteristics similar to the matched cohort of this study (median age 81 with higher comorbidity and functional impairment burdens, the BCSS survival differential disappears at least out to 4–5 year follow- up, suggesting that for those with less than 5-year predicted life-expectancy (>90 years or>85 with comorbidities or frailty) individualised decision making regarding PET versus S+ET may be appropriate and safe to offer.

Source: European Journal of Cancer - November 18, 2020 Category: Cancer & Oncology Authors: Lynda Wyld, Malcolm W.R. Reed, Jenna Morgan, Karen Collins, Sue Ward, Geoffrey R. Holmes, Mike Bradburn, Stephen Walters, Maria Burton, Esther Herbert, Kate Lifford, Adrian Edwards, Alistair Ring, Thompson Robinson, Charlene Martin, Tim Chater, Kirsty Pem Tags: Clinical Trial Source Type: research