New insights into Glioblastoma invasiveness

(Luxembourg Institute of Health) Researchers from the NORLUX Neuro-Oncology Laboratory at the LIH Department of Oncology (DONC) explored the molecular mechanisms responsible for the ability of Glioblastoma (GBM) to infiltrate and spread to healthy brain tissue. They brought forward the novel role of protein ZFAND3 in promoting the transcription of several genes that stimulate the invasion of GBM cells in the surrounding parenchyma. The findings, which carry significant implications for the development of novel therapeutic strategies against GBM, were published in the international journal Nature Communications.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news