Letter to the Editor: Do biomarkers of COVID-19 severity simply reflect a stress response in type 2 diabetes: Biomarker response to hypoglycemia

Type 2 diabetes (T2D) is associated with high risk for acquiring SARS-Cov-2 infection, severe disease, acute respiratory distress syndrome and increased mortality [1,2] A recent publication reported five predictive COVID-19 severity markers that included CCL17 which was expressed in low levels in severe/critical patients at an early phase of infection; IFN λ, IL6, IP10, and CXCL9 values surged and then dropped suddenly before the development of severe disease requiring oxygen support [3]. This suggested that CCL17 may be a useful first triage marker and the other reported proteins may help to predict severe disease onset [3].
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Tags: Correspondence Source Type: research