Increased Association of Deamidated αA-N101D with Lens membrane of transgenic αAN101D vs. wild type αA mice: potential effects on intracellular ionic imbalance and membrane disorganization

We have generated two mouse models, in one by inserting the human lens αAN101D transgene in CRYαAN101D mice, and in the other by inserting human wild-type αA-transgene in CRYαAWT mice. The CRYαAN101D mice develop...

Source: BMC Ophthalmology - December 10, 2020 Category: Opthalmology Authors: Om Srivastava, Kiran Srivastava, Roy Joseph and Landon Wilson Tags: Research article Source Type: research