Optimization of spinal manipulative therapy protocols: a factorial randomized trial within a multiphase optimization framework

Low back pain (LBP) is among the most common health conditions and a leading cause of disability globally.1, 38 The adverse societal impacts of ineffective LBP management are increasingly recognized. Back pain is the most costly health condition in the United States and is the most common diagnosis for which opioids are prescribed.22, 70 Practice guidelines recommend nonpharmacological treatment (NPT) for pain conditions including LBP.18, 23, 58 While many NPTs are effective for LBP, the magnitude of effects are small and highly heterogeneous within groups of patients.

Source: The Journal of Pain - December 9, 2020 Category: Materials Science Authors: Julie M. Fritz, Jason Sharpe, Tom Greene, Elizabeth Lane, Maliheh Hadizadeh, Molly McFadden, Douglas Santillo, Jedidiah Farley, Jake Magel, Anne Thackeray, Gregory Kawchuk Tags: Original Reports Source Type: research