Susceptibility Vessel Sign in Deep Perforating Arteries in Patients with Recent Small Subcortical Infarcts

Recent small subcortical infarcts (RSSI) are the neuroimaging evidence of an acute infarction resulting from the occlusion of deep perforating arteries of the brain. RSSIs are considered one of the main radiological features of cerebral small vessel disease on magnetic resonance imaging (MRI), along with other chronic markers such as white matter hyperintensities (WMH), lacunae, cerebral microbleeds, enlarged perivascular spaces, and brain atrophy.1 The pathophysiology of cerebral small vessel disease is still unknown, but many mechanisms seem to be implied, such as arteriosclerosis, hypoperfusion, blood-brain barrier leakage, and endothelial dysfunction, among others.

Source: Journal of Stroke and Cerebrovascular Diseases - October 31, 2020 Category: Neurology Authors: Salvatore Rudilosso, Marta Olivera, Diana Esteller, Carlos Laredo, Sergio Amaro, Laura Llull, Arturo Ren ú, Víctor Obach, Víctor Vera, Alejandro Rodríguez, Jordi Blasco, Antonio López-Rueda, Xabier Urra, Ángel Chamorro Source Type: research