Neurodevelopmental Outcomes after Premedication with Atropine/Propofol versus Atropine/Atracurium/Sufentanil for Neonatal Intubation: 2 Year Follow Up of a Randomized Clinical Trial

Premedication for nonemergent tracheal intubation in newborn infants is strongly recommended to decrease pain and adverse events related to the procedure1. However, there is no consensus on which drugs to use1-3. A short-acting opioid associated with a muscle-blocker is recommended by several academic societies2,3 but prevents titration and assessment of proper sedation and analgesia4. Propofol is a short-acting anesthetic that has been proposed as an alternative1,5,6. Reported advantages of propofol are preservation of spontaneous ventilation, less frequent oxygen desaturation, possible titration and faster intubation4-6.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Brief Reports Source Type: research