The gut –brain axis in irritable bowel syndrome and inflammatory bowel disease

Research increasingly demonstrates the bidirectional communication between gut microbiota and the brain, enhancing the role of gut microbiota modulation in the treatment of central nervous system (CNS) disorders. The first five years of life are extremely important as it affects the development of gut microbiota, immune system and, consequently, the onset of psychometric alterations, particularly in genetically predisposed individuals.In this review, we focus on the link between specific microbial genera, gastrointestinal (GI) disorders, anxiety and depression and on the effects of different therapeutic strategies for mood disorders on gut microbiota.

Source: Digestive and Liver Disease - December 7, 2020 Category: Gastroenterology Authors: Angela Ancona, Claudia Petito, Irene Iavarone, Valentina Petito, Linda Galasso, Alessia Leonetti, Laura Turchini, Daniela Belella, Daniele Ferrarrese, Giovanni Addolorato, Alessandro Armuzzi, Antonio Gasbarrini, Franco Scaldaferri Tags: Review Article Source Type: research