EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study

The independent effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid mediators, including the specialized pro-resolving lipid mediators (SPM), remain unstudied. Therefore, we compared the effects of EPA and DHA supplementation on monocyte inflammatory response and plasma polyunsaturated fatty acids (PUFA) SPM lipidome.

Source: Atherosclerosis - December 7, 2020 Category: Cardiology Authors: Jisun So, Dayong Wu, Alice H. Lichtenstein, Albert K. Tai, Nirupa R. Matthan, Krishna Rao Maddipati, Stefania Lamon-Fava Source Type: research