Modeling Multi-organ Infection by SARS-CoV-2 Using Stem Cell Technology.
Modeling Multi-organ Infection by SARS-CoV-2 Using Stem Cell Technology.
Cell Stem Cell. 2020 Dec 03;27(6):859-868
Authors: Simoneau CR, Ott M
Abstract
SARS-CoV-2, the virus causing the current COVID-19 pandemic, primarily targets the airway epithelium and in lungs can lead to acute respiratory distress syndrome. Clinical studies in recent months have revealed that COVID-19 is a multi-organ disease causing characteristic complications. Stem cell models of various organ systems-most prominently, lung, gut, heart, and brain-are at the forefront of studies aimed at understanding the role of direct infection in COVID-19 multi-organ dysfunction.
PMID: 33275899 [PubMed - as supplied by publisher]
Source: Cell Stem Cell - Category: Stem Cells Authors: Simoneau CR, Ott M Tags: Cell Stem Cell Source Type: research
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