Clinical and genomic factors associated with seizures in meningiomas.

CONCLUSIONS: Seizures are relatively common at meningioma presentation. While NF2-mutated tumors are significantly associated with preoperative seizures, the association appears to be mediated through edema and atypical histology. Patients who undergo radiation and/or have a recurrence are at risk for postoperative seizures, regardless of the extent of resection. Preoperative seizures may indeed portend a more potentially aggressive molecular entity and challenging clinical course with a higher risk of recurrence. PMID: 33276341 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33276341?dopt=Abstract

Source: Journal of Neurosurgery - December 4, 2020 Category: Neurosurgery Authors: Gupte TP, Li C, Jin L, Yalcin K, Youngblood MW, Miyagishima DF, Mishra-Gorur K, Zhao AY, Antonios J, Huttner A, McGuone D, Blondin NA, Contessa JN, Zhang Y, Fulbright RK, Gunel M, Erson-Omay Z, Moliterno J Tags: J Neurosurg Source Type: research