Presence of allele CYP3A4 & #42;16 does not have any bearing on carbamazepine-induced adverse drug reactions in North Indian people with epilepsy
CONCLUSION: CYP3A4*16 allele is not represented significantly in North Indian people with CBZ-induced dose-related side effects.
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Vivek Kumar Garg Manoj Kumar Goyal Madhu Khullar Biman Saikia Bikash Medhi Ajay Prakash Nandita Prabhat Naresh Tandyala Karthik Vinay Mahesh Parampreet S Kharbanda Sudesh Prabhakar Manish Modi Vivek Lal Ritu Shree Julie Sachdeva Source Type: research