Effect of SARS-CoV-2 coinfection was not apparent on the dynamics of chronic hepatitis B infection.

Effect of SARS-CoV-2 coinfection was not apparent on the dynamics of chronic hepatitis B infection.
Virology. 2020 Nov 28;553:131-134
Authors: Yu R, Tan S, Dan Y, Lu Y, Zhang J, Tan Z, He X, Xiang X, Zhou Y, Guo Y, Deng G, Chen Y, Tan W
Abstract
In patients coinfected with SARS-CoV-2 and HBV, liver injury was common. However, the interactions between SARS-CoV-2 and HBV coinfection remained unknown. Sixty-seven COVID-19 patients from the previous cohort were enrolled and classified into 2 groups (7 with HBsAg+ and 60 with HBsAg-). The association of HBV- and SARS-CoV-2-related markers were analyzed. During the acute course of SARS-CoV-2 infection, markers of HBV replication did not extensively fluctuate during SARS-CoV-2 infection. Coinfection with HBV did not extend the viral shedding cycle or incubation periods of SARS-CoV-2. Effects of SARS-CoV-2 on the dynamics of chronic HBV infection seemed not apparent. SARS-CoV-2 infection would not be the source of HBV reactivation in these individuals.
PMID: 33276282 [PubMed - as supplied by publisher]

Source: Virology - November 28, 2020 Category: Virology Authors: Yu R, Tan S, Dan Y, Lu Y, Zhang J, Tan Z, He X, Xiang X, Zhou Y, Guo Y, Deng G, Chen Y, Tan W Tags: Virology Source Type: research