Penicillin and cephalosporin cross-reactivity: role of side chain and synthetic cefadroxil epitopes
ConclusionsCross-reactivity with CX in AX allergic patients is 35%, being ST not enough for prediction. R1, although critical for recognition, is not the unique factor. The synthetic determinants of CX, 1-(HOPhG-Ser-Bu) and 2-(pyrazinone) are promising tools for determining in vitro cross-reactivity to CX in AX allergic patients.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
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